As far as Semiautomatic Handguns go I would have to go with a SIG-Sauer P226. It's a common highly reliable handgun that when set up with something like an M6 laser/flashlight and a sound supressor makes for an effective and quiet backup weapon.
As far as revolvers go while not as common as a .357 I have a preferance for the .44 magnum as it's flat shooting enough that an experianced user can shoot out to 300+ yards.
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